Nucleic Acid Synthesis
Cayman Chemical 3-Deaza-2-deoxyadenosIn 10mg
Strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM; can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure and function
Cytek Biosciences Inc APO-BrdU Kit Panels Kit
Product Name: APO-BrdU™ Kit
Cytek Catalog Number: TNB-6671-KIT
Product Class: Kits and Panels
Type: Kit
Size: 60 Tests
Medchemexpress LLC 1alpha, 24, 25-Trihydroxy VD2 | 457048-34-9 | C28H44O4 | 1 MG
1alpha, 24, 25-Trihydroxy VD2 is a vitamin D analog.
- Purity of 98.21%
- Molecular weight of 444.65
- Appears as a white to yellow solid
- For research use only
- Optimal storage at -20°C, protected from light and stored under nitrogen
- Soluble in DMSO at 12.5 mg/mL
Cayman Chemical nurofIbrIlary Tngle BODIPY
A fluorescent probe for neurofibrillary tangles; binds to tau-K18 aggregates in a cell-free assay (Kd = 16.8 nM) and is 2.17-fold selective for tau-K18 over Aβ42 aggregates; has been used to label NFTs in postmortem hippocampus from patients with Alzheimer’s disease; has been used to identify tauopathy in vivo and ex vivo in transgenic human tauP301L-expressing mice with a lower signal occurring in the brain of wild-type mice; ex/em = 570-600/710-774 nm in methylene chloride, THF, methanol, DMSO, and PBS
Apexbio Technology LLC 6-Thio-dG 789-61-7 5mg
6-Thio-2 -deoxyguanosine (6-Thio-dG CAS 789-61-7) is a nucleoside analogue that functions as a telomerase-mediated telomere targeting agent In telomerase-positive cancer cells 6-Thio-dG is incorporated into telomeric DNA inducing rapid telomere dysfunction independent of direct telomerase inhibition which leads to growth arrest and cell death In vitro cancer cell lines exhibit IC50 values ranging from 0 7 to 2 9 M indicating high sensitivity to the compound Normal cells with telomerase-silent status show minimal morphological effects upon 6-Thio-dG exposure In vivo 6-Thio-dG administration inhibits tumor growth and reduces proliferation markers in xenograft models The compound is valuable for investigating telomere biology and as a tool to evaluate telomerase-dependent therapeutic strategies in cancer research
Biotium Proliferation Viability Assays Enzyme Substrates Luciferase Substrates CellTiter Glo 1/EA
A luciferase-based ATP cell viability assay for high-throughput luminescence detection in microplates The homogenous assay offers high sensitivity wide dynamic range of over 3-4 orders of magnitude and long-lasting signal with a half-life of over 5 hours
![eMolecules 10017-66-0 | Alpha-Pseudouridine | Broadpharm244.203 | C9H12N2O6 | 0.000 | OC[C@H]1O[C@@H]([C@H](O)[C@@H]1O)c1c[nH]c(=O)[nH]c1=O | 100mg | 761707695](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502459962.PNG-250.jpg)
eMolecules 10017-66-0 | Alpha-Pseudouridine | Broadpharm244.203 | C9H12N2O6 | 0.000 | OC[C@H]1O[C@@H]([C@H](O)[C@@H]1O)c1c[nH]c(=O)[nH]c1=O | 100mg | 761707695
Alpha-Pseudouridine | Broadpharm | 10017-66-0244.203 | C9H12N2O6 | 0.000 | OC[C@H]1O[C@@H]([C@H](O)[C@@H]1O)c1c[nH]c(=O)[nH]c1=O | 100mg | 761707695
Medchemexpress LLC 3-Methyluridine | 2140-69-4 | 99.1% | 258.23 | 25 MG
3-Methyluridine | 2140-69-4 | 99.1% | 258.23 | 25 MG